Table 2.

HOD patient baseline data. The characteristics of ten patients with HOD development on MRI are shown. Age is defined as age at the time of the initial diagnosis of the brain tumor. Diagnosis is based on histopathology. The surgical approaches are listed as taken from the OR-reports. Latency resection to HOD is defined as time in between the first surgical operation to first radiological signs of HOD on MRI, months are rounded up for >2 weeks. HOD symptoms are defined as palatal tremor, Holmes-tremor and pendular nystagmus. Tumor size volumes were calculated using the ABC/2 estimation formula based on MRI-data [40]. Abbreviations: Pat. = Patient; mo. = months; CMS = cerebellar mutism syndrome; m = male; f = female; SCP = superior cerebellar peduncle.

Pat.	Age, Sex	Diagnosis WHO°	HOD Side	Tumor Localization	Operative Approach	Lesion within GMT	Adjuvant RCT	Tumor Size (mm) [Volume]	Time Lesion to HOD	CMS
1	20, f	pilocytic astrocytoma I°	right	4th ventricle	paravermal trans-cerebellar	both dentate nuclei (left > right)	none	63 × 42 × 36 [48 cm3]	2 mo.	no
2	60, f	pilocytic astrocytoma I°	right	4th ventricle to vermis	paravermal trans-cerebellar	both dentate nuclei (left > right)	none	42 × 63 × 56 [74 cm3]	8 mo.	no
3	32, m	pilocytic astrocytoma I°	left	4th ventricle to vermis	paravermal trans-cerebellar	right dentate nucleus	none	37 × 40 × 30 [22 cm3]	6 mo.	no
4	14, f	pilocytic astrocytoma I°	right	cerebellar vermis	paravermal trans-cerebellar	both dentate nuclei	none	58 × 57 × 57 [94 cm3]	4 mo.	no
5	17, f	pilocytic astrocytoma I°	right	4th ventricle	paravermal trans-cerebellar	left dentate nucleus	none	33 × 34 × 39 [22 cm3]	4 mo.	no
6	35, m	ependymoma II°	left	4th ventricle	midline telovelar	both dentate nuclei (right > left)	none	42 × 15 × 20 [6 cm3]	3 mo.	no
7	14, m	medulloblastoma IV°	right	4th ventricle	midline transvermian	left dentate nucleus	yes	34 × 47 × 37 [30 cm3]	3 mo.	no
8	34, m	medulloblastoma IV°	bilateral	4th ventricle	midline telovelar	both dentate nuclei	yes	46 × 35 × 35 [28 cm3]	10 mo.	no
9	9, m	medulloblastoma IV°	bilateral	4th ventricle and cerebellum	paravermal trans-cerebellar	both dentate nuclei, left SCP	yes	53 × 37 × 48 [47 cm3]	4 mo.	yes
10	40, m	medulloblastoma IV°	right	4th ventricle	paravermal trans-cerebellar and telovelar	left dentate nucleus	yes	31 × 21 × 27 [9 cm3]	3 mo.	no