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In situ hybridization of miR-181b and the respective pre-miRNA on tissue sections from tonsil of non-cancer patients and from lymph nodes of CLL patients. One representative picture of a tissue section of tonsil is shown (upper left) and lymph node sections from 5 CLL patients at 250X and 400X magnifications. Bold arrows indicate the nuclear localization, while slim arrows the cytoplasmic localization.
