APRIL |
a proliferation-inducing ligand |
BAFF |
B-cell activating factor |
Bcl-6 |
B-cell lymphoma 6 |
Blimp-1 |
B lymphocyte-induced maturation protein-1 |
BTK |
Bruton tyrosine kinase t |
CCL3 |
C-C chemokine ligand type 3 |
CCL4 |
C-C chemokine ligand type 4 |
CCR5 |
C-C chemokine receptor type 5 |
CCR7 |
C-C chemokine receptor type 7 |
CTLA-4 |
cytotoxic T-lymphocyte-associated protein 4 |
CXCL1 |
C-X-C motif chemokine type 1 |
CXCL2 |
C-X-C motif chemokine type 2 |
CXCL9 |
C-X-C motif chemokine type 9 |
CXCL10 |
C-X-C motif chemokine type 10 |
CXCL12 |
C-X-C motif chemokine type 12 |
CXCL13 |
C-X-C motif chemokine type 13 |
CXCR3 |
C-X-C motif chemokine receptor type 3 |
CXCR5 |
C-X-C motif chemokine receptor type 5 |
CCL3 |
chemokine (C-C motif) ligand 3 |
CCL4 |
chemokine (C-C motif) ligand 4 |
CCL19 |
chemokine (C-C motif) ligand 19 |
CCL21 |
chemokine (C-C motif) ligand 21 |
DCs |
dendritic cells |
ECM |
extracellular matrix |
ESSDAI |
EULAR Sjögren’s syndrome disease activity index |
fDCs |
follicular dendritic cells |
FoxP3 |
forkhead box protein transcription factor P3 |
GATA-3 |
GATA Binding Protein 3 |
GITR |
glucocorticoid-induced TNFR-related protein |
HLA |
human leukocyte antigen |
ICAM-1 |
intercellular adhesion molecule 1 |
IC |
immune-complexes |
ICOS |
Inducible T-cell COStimulator |
Id3 |
inhibitor of DNA binding 3 |
Baff |
Interferon |
IFN-γ |
interferon gamma |
IL |
Interleukin |
IL1R1 |
interleukin-1 receptor type 1 |
IL-2Rα |
IL-2 receptor α |
ILC |
innate Lymphoid Cells |
iNKT |
invariant natural killer T cells |
LNs |
lymph nodes |
MAIT |
mucosal-associated invariant T cells |
MALT |
mucosa-associated lymphoid tissue |
MSGs |
minor salivary glands |
MHC-I |
major histocompatibility complex class I |
MHC-II |
major histocompatibility complex class II |
MMPs |
Metalloproteases |
MR1 |
MHC-I-related molecule 1 |
MZ |
marginal zone |
NFAT-2 |
nuclear Factor of activated T cells 2 |
NK |
natural killer cells |
NKT |
natural killer T cells |
NOD |
non-obese diabetic |
PD-1 |
programmed death-ligand 1 |
pDCs |
plasmacytoid dendritic cells |
pSS |
primary Sjögren’s syndrome |
RA |
rheumatoid arthritis |
RORγt |
retinoic acid-related orphan receptor gamma t |
SGs |
salivary glands |
SGECs |
salivary glands epithelial cells |
SLE |
systemic lupus erythematosus |
SS |
Sjögren’s syndrome |
sSS |
secondary Sjögren’s syndrome |
ST2 |
suppression of tumorigenicity 2 |
STAT |
signal transducer and activator of transcription |
TBX21 or T-bet |
T-Box Transcription Factor 21 |
TCR |
T cell receptor |
Tfh |
T follicular helper |
Tfr |
follicular regulatory T cells |
TGFβ |
transforming growth factor beta |
Th1 |
type 1 helper cells |
Th17 |
type 17 helper cells |
TLR |
toll-like receptor |
TNFα |
tumor necrosis factor alpha |
Tregs |
T-regulatory cells |
VCAM-1 |
vascular cell adhesion molecule |
VEGF-C |
vascular endothelial growth factor C |
VEGFR-3 |
vascular endothelial growth factor receptor 3 |
ZO-1 |
zonula occludens 1 |