Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Jan 7;13(1):73. doi: 10.3390/pharmaceutics13010073

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Effect of MLo1302 treatment on DNA methyltransferases (DNMTs) expression and on DNA methylation profile. (A) Western blot for DNMTs in cell lines treated with MLo1302. Beta-actin is used as normalizer. Band densitometry graphs are provided (treated versus control); (B) Dotblot for 5 mC in cell lines treated with MLo1302, and respective quantification. Results are normalized to Sybergreen; (C) Immunofluorescence for 5 mC in cell lines treated with MLo1302, and respective quantification; (D) Immunofluorescence for 5 hmC in NCCIT cell line treated with MLo1302; (E) RASSF1A promoter DNA methylation in cell lines treated with MLo1302. Results are normalized to beta-actin. * p < 0.05; ** p < 0.01; *** p < 0.001.