Table 2.
Relationships between total cfDNA and clinical characteristics in all studied subjects.
| Parameter | Rho | 95% CI | p |
|---|---|---|---|
| Age (years) | 0.043 | −0.086 to 0.170 | 0.5032 |
| Systolic blood pressure (mm Hg) | 0.420 | 0.311 to 0.519 | <0.0001 |
| Diastolic blood pressure (mm Hg) | 0.374 | 0.260 to 0.478 | <0.0001 |
| Heart rate (bpm) | −0.144 | −0.265 to −0.018 | 0.0213 |
| Creatinine (μM) | 0.031 | −0.122 to 0.182 | 0.6843 |
| Proteinuria (mg/24 h) | 0.093 | −0.111 to 0.290 | 0.3568 |
| Hematocrit (%) | 0.061 | −0.074 to 0.194 | 0.3595 |
| Hemoglobin (g/dL) | 0.056 | −0.080 to 0.189 | 0.4083 |
| White blood cells (×103/mm3) | −0.041 | −0.185 to 0.104 | 0.5672 |
| Neutrophils (% of WBC) | 0.079 | −0.091 to 0.244 | 0.3498 |
| Platelets (×103/mm3) | −0.172 | −0.310 to 0.027 | 0.0167 |
| Fasting glucose (g/dL) | 0.103 | −0.044 to 0.245 | 0.1577 |
| Alanine transaminase (U/L) | 0.154 | −0.047 to 0.342 | 0.1213 |
| Aspartate aminotransferase (U/L) | 0.188 | 0.033 to 0.333. | 0.0146 |
| Lactate dehydrogenase (U/L) | 0.334 | 0.028 to 0.582 | 0.0288 |
| Gestational age at enrollment (weeks) | −0.046 | −0.169 to 0.077 | 0.4493 |
| Body mass index at enrollment (kg/m2) | 0.092 | −0.035 to 0.216 | 0.1443 |
| Gestational age at delivery (weeks) | −0.181 | −0.307 to −0.049 | 0.0058 |
| Newborn weight (g) | −0.256 | −0.375 to −0.129 | <0.0001 |
| Placental weight (g) | −0.039 | −0.174 to 0.098 | 0.5699 |
Values are the Spearman’s Rho, 95% confidence interval (CI), and p values for the correlation between plasma total cell-free DNA concentration (cfDNA, ng/mL) and the respective clinical parameter.