Table 1.
Dynamics of protein phosphorylation pathways regulated by hypoxia, acute, and chronic iron deficiency. Functional activity is summarized either as increased, decreased, or unchanged (blank).
| CELLULAR FUNCTIONS | HYPOXIA | ACUTE ID | CHRONIC ID |
|---|---|---|---|
| CELL METABOLISM | Increase | Decrease | Decrease |
| CELL CYCLE CONTROL | Decrease | Increase | Increase |
| DNA DAMAGE AND REPAIR | Decrease | Increase | |
| INFLAMMATORY RESPONSE | Decrease | Increase | Decrease |
| METAL ION HOMEOSTASIS | Increase | Increase | |
|
EPIGENETIC PROCESSES
Histone methylation DNA methylation |
Increase |
Decrease |
Decrease |