Table 2.
Microsphere (MS) formulations and amount of tested MSs in each assay.
| Formulation | GDNF (µg) | BDNF (µg) | Vit E(µL) | Toxicity Assay | Wound Closure Assay | Apoptosis Assay | Safety In Vivo | RGCs Survival | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MSs (µg) | Naming | MSs (µg) | Naming | MSs (µg) | Naming | MSs (µg) | Naming | MSs (µg) | Naming | ||||
| MSs-GE20 | 20 | - | 20 | 40 | MSs-GE20_40 | 40 | MSs-GE20_40 | 40 | MSs-GE20_40 | - | - | ||
| MSs-GBE40 | 36 | 20 | 40 | 20 | MSs-GBE40_20 | 20 | MSs-GBE40_20 | 20 | MSs-GBE40_20 | 80 | MSs-GBE40_80 | 20 | MSs-GBE40_20 |
| MSs | - | - | - | 20/40 | MSs_20/MSs_40 | 20/40 | MSs_20/MSs_40 | 20 | MSs_20 | 80 | MSs_80 | 20 | MSs_20 |
| MSs-E20 | - | - | 20 | 20/40 | MSs-E20_20/MSs-E20_40 | 40 | MSs-E20_40 | 20 | MSs-E20_40 | - | - | - | - |
| MSs-E40 | - | - | 40 | 20/40 | MSs-E40_20/MSs-E40_40 | 20 | MSs-E40_20 | 20 | MSs-E40_20 | 80 | MSs-E40_80 | - | - |