Table 6.

Correlations between liver fibrosis biomarkers and three different cardiovascular risk (CVR) scores.

	SCORE			Progetto CUORE			FRS
	All	Viral CLD	NAFLD	All	Viral CLD	NAFLD	All	Viral CLD	NAFLD
AAR	0.302 *	0.261 †	0.406 *	0.302 *	0.340 *	0.325 †	0.252 *	0.166 §	0.401 *
APRI	0.208 *	0.234 †	0.260 *	0.145 §	0.156	0.375 *	0.114	0.124	0.407 *
FIB-4	0.462 *	0.476 *	0.499 *	0.402 *	0.399 *	0.560 *	0.342 *	0.319 *	0.584 *
Forns	0.468 *	0.454 *	0.544 *	0.437 *	0.370 *	0.568 *	0.445 *	0.453 *	0.532 *
NFS	_	_	0.593 *	_	_	0.658 *	_	_	0.702 *
BARD	_	_	0.449 *	_	_	0.471 *	_	_	0.540 *
HFS	_	_	0.509 *	_	_	0.643 *	_	_	0.679 *

Data are expressed as Pearson’s r correlation coefficients for all correlations except for those with BARD score which are expressed as Spearman’s rho (ρ). * p < 0.001 ^† p < 0.005 ^§ p < 0.05. The absence of any symbols denotes “p not significant”. Abbreviations: AAR, AST to ALT ratio; ALT, alanine aminotransferase; APRI, AST to Platelet Ratio Index; AST, aspartate aminotransferase; BARD, BMI AST/ALT Ratio Diabetes; CLD, chronic liver disease; CVR, cardiovascular risk; FIB-4, fibrosis-4; FRS, Framingham risk score; HFS, Hepamet fibrosis score; NAFLD, nonalcoholic fatty liver disease; NFS, NAFLD fibrosis score.