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Hoechst 33342 dye extrusion in HeLa cells stably expressing the WT and Q141K variants of ABCG2. Different concentrations of ivermectin (A), lopinavir (B), ritonavir (C), and remdesivir (D) were used to determine their effect on ABCG2 function. Data on the graphs show the average of three independent experiments, +/− SD values.
