Table 3.

Significantly over-represented pathways found for the liver tissue of Boran and N’Dama (p-adjusted $<0.05$).

	Liver
	Pathway Name	Hit Names	Adjusted p-Value
Boran	Cellular responses to external stimuli	Arnt, Fos, Hif1a, Hsf1	4.64 × 10${}^{-4}$
	Regulation of beta-cell development	Foxo1, Hnf4g, Nkx2.2	0.0032
	Regulation of Hypoxia-inducible Factor (HIF) by oxygen	Arnt, Hif1a	0.0033
	Cellular response to hypoxia	Arnt, Hif1a	0.0033
	Signaling by TGF-beta Receptor Complex	Myc, Smad3, Smad4	0.0036
	Signaling by TGF-beta family members	Myc, Smad3, Smad4	0.0063
	Signaling by NOTCH1	Hif1a, Myc	0.0105
	Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer	Myc, Smad4	0.0147
	Signaling by NOTCH	Hif1a, Myc	0.0349
	Interleukin-1 family signaling	Nfkb1, Smad3	0.0371
	Cellular Senescence	Fos, Jun	0.0416
N’Dama	PTEN Regulation	Atf, Jun	0.0025
	Activation of HOX genes during differentiation	Hoxa4, Jun, Meis1	0.0036
	Activation of anterior HOX genes in hindbrain development during early embryogenesis	Hoxa4, Jun, Meis1	0.0036
	BMAL1:CLOCK, NPAS2 activates circadian gene expression	Dbp, Ppara	0.0161
	PIP3 activates AKT signaling	Atf, Jun	0.0229
	Transcriptional regulation of pluripotent stem cells	Pbx1, Pou5f1	0.0229
	Intracellular signaling by second messengers	Atf2, Jun	0.0280
	Transcriptional regulation by RUNX2	Sox9, Stat1	0.0364
	Transcriptional regulation of white adipocyte differentiation	Pparg, Rxra	0.0424
	Circadian Clock	Dbp, Ppara	0.0488