Table 1.

Main features of the described antibody-derived peptides.

Peptide	Origin	Sequence	GRAVY Value 1	Net Charge	Structure	Antifungal Mechanism of Action	Ref.
KP	Variable region of a recombinant scFv-Ab	AKVTMTCSAS	0.530	1+	β-sheet	Interaction with cell wall molecules, intracellular targets	[52]
N10K	IgG Fc region	NQVSLTCLVK	0.610	1+	β-sheet	Apoptosis/ autophagy induction	[55]
T11F	IgM Fc region	TCRVDHRGLTF	−0.382	3+	PPII helix	Membrane binding and disruption	[56]
L12P	Translated product of IGLJ1 gene	LCLRNWDQGHRP	−1.292	2+	n.d. 2	Membrane disruption	[57]
L18R	Translated product of IGHJ2 gene	LLVLRSLGPWHPGHCLLR	0.467	4+	n.d.	Apoptosis induction	[57]
K40H	IgM Fc region	KSTKLTCLVTDLTTYDSVpTIpSWTRQNGEAVKTHTNISESH	−0.568	0	n.d.	Effect on actin dynamics	[58]

¹ Grand average of hydropathy (GRAVY) calculated by the ExPASy tool ProtParam; ² n.d., not determined.