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. 2021 Jan 8;22(2):592. doi: 10.3390/ijms22020592
4E-BP1 Eukaryotic Translation Initiation Factor 4E
AKT Protein Kinase B
ALL Acute lymphoblastic leukemia
AML Acute myeloid leukemia
ATP Adenosine triphosphate
Avg Average
B-ALL B-acute lymphoblastic leukemia
BCL-2 BCL2 Apoptosis Regulator
BCL-6 BCL6 Transcription Repressor
BCR B-cell receptor
BCR- B-cell receptor negative
BCR+ B-cell receptor positive
BIM Bcl-2-like protein 11
BLNK B Cell Linker
BTK Bruton Tyrosine Kinase
CD22 B-Lymphocyte Cell Adhesion Molecule
CD79B B-Cell Antigen Receptor Complex-Associated Protein Beta Chain
CDC25C Cell Division Cycle 25C
CDK1 Cyclin Dependent Kinase 1
CLL Chronic lymphocytic leukemia
DAPP1 Dual Adaptor Of Phosphotyrosine And 3-Phosphoinositides 1
DLBCL Diffuse large B-cell lymphoma
DN Dominant negative
Ento Entospletinib
ERK Extracellular signal-regulated kinases
FDA Food and Drug Administration
FL Follicular lymphoma
FOXO1 Forkhead Box O1
GoF Gain-of-function
GS-9973 Entospletinib, SYK inhibitor
GSK3β Glycogen Synthase Kinase 3 Beta
IC50 Half maximal inhibitory concentration
Igµ Immunoglobulin heavy chains
IgG Immunoglobulin G
IgM Immunoglobulin M
Ig-α Immunoglobulin (Ig)α cytoplasmic domain
Ig-β Immunoglobulin (Ig)β cytoplasmic ddomain
IL7R Interleukin 7 Receptor
ITAMs Immunoreceptor tyrosine-based activation motifs
LAT2 Linker For Activation Of T Cells Family Member 2
LoF Loss-of-function
MAP Mitogen-activated protein
MCL Mantle cell lymphoma
MEK Mitogen-activated protein kinase kinase
MFI Mean fluorescence intensity
MLL Mixed lineage leukemia
p Phospho
p53 Tumor Protein P53
p63 Tumor protein P63
p73 Tumor protein P73
PCA Principle component analysis
PI3K Phosphoinositide 3-kinase
PRT318 SYK Inhibitor
PTPN6 Protein Tyrosine Phosphatase Non-Receptor Type 6
R406 SYK Inhibitor
Raf RAF proto-oncogene serine/threonine-protein kinase
RAS Rat sarcoma
RPS6KB1 Ribosomal Protein S6 Kinase B1
S Serine
Ser Serine
SHP-1 Protein Tyrosine Phosphatase Non-Receptor Type 6
SPRY2 Sprouty RTK Signaling Antagonist 2
SYK Spleen tyrosine kinase
TAC Transcriptome Analysis Console
TCF3-PBX1 Fusion gene Transcription Factor 3 and PBX Homeobox 1
TNF Tumor necrosis factor
TP53 Tumor Protein P53
Tyr Tyrosin
VEGFA Vascular Endothelial Growth Factor A
wt Wild type
Y Tyrosin