Figure 7.

Analysis of DEGs implicated in neuroinflammatory pathways and the activation of microglia or astrocytes in mature CNS cultures. Expression analyses of DEGs in ZIKV-infected samples versus mock-infected samples at 4 dpi was performed using IPA and filtered to only include genes reported to be involved in neuroinflammation, microglia activation, or astrocyte activation (nervous system tissues, CNS cell lines, and neuroblastoma cell lines). Displayed DEGs were grouped and categorized using the canonical pathways and disease and function tool. Log2FC: Log2 fold change expression value.