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. 2021 Jan 12;22(2):675. doi: 10.3390/ijms22020675
AAV adeno-associated virus
ALA δ-aminolaevulinic acid
ALAD δ-aminolaevulinic acid dehydratase
ALAS δ-aminolaevulinic acid synthase
CYP cytochrome P450-dependent oxidase
DPM Dipyrromethane
E, E(holo) holoenzyme
ES1–4 Enzyme-substrate intermediates, with 1 to 4 substrate units
GABA γ-aminobutyric acid
GATs GABA transporters
HMB 1-hydroxymethylbilane
HMBS Hydroxymethylbilane synthase
PBG Porphobilinogen
PEPT2 peptide transporter 2
PGC-1α peroxisome proliferator-activated receptor γ coactivator 1α
ROS reactive oxygen species
siRNA small interference RNA
T m half-denaturing temperature
UPS ubiquitin-proteasome system