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. 2021 Jan 11;22(2):664. doi: 10.3390/ijms22020664

Figure 7.

Figure 7

Protease inhibitors lower the TGF-β activity in the supernatant of OraGRAFT® Prime. Gingival fibroblasts were exposed to aqueous supernatants of OraGRAFT® Prime in the absence (SF) or presence (SFP) of the protease inhibitors. The expression of (A) IL11, (B) NOX4, and (C) PRG4 was decreased significantly by protease inhibitors. The expression of IL11, NOX4, and PRG4 was measured by quantitative RT-PCR. N = 4. Statistic is a paired t-test.