Table 7.
Trimmed effect size of probiotics on inflammatory bowel disease in murine model.
| Items | df | Fixed Effect Model | Random Effect Model | Heterogeneity | ||||
|---|---|---|---|---|---|---|---|---|
| ES | p-Value | ES | p-Value | Q (p-Value) | I2 (%) | τ2 | ||
| Total cholesterol (blood) | 86 | −1.1096 | <0.0001 | −1.2079 | <0.0001 | 686.36 (<0.0001) | 87.5 | 3.6291 |
| Triglyceride (blood) | 78 | −0.2142 | 0.0029 | −0.2935 | 0.2360 | 878.84 (<0.0001) | 91.1 | 4.2254 |
| LDL-cholesterol (blood) | 64 | −1.1291 | <0.0001 | −1.2373 | <0.0001 | 551.97 (<0.0001) | 88.4 | 4.2350 |
| HDL-cholesterol (blood) | 52 | 0.0607 | 0.4912 | −0.1870 | 0.5174 | 521.81 (<0.0001) | 90.0 | 3.7407 |
| Total cholesterol (liver) | 42 | −1.7190 | <0.0001 | −1.8509 | <0.0001 | 367.01 (<0.0001) | 88.6 | 5.8208 |
| Triglyceride (liver) | 31 | −1.4703 | <0.0001 | −1.6805 | 0.0004 | 314.64 (<0.0001) | 90.1 | 6.2275 |
| Total cholesterol (feces) | 31 | 1.2437 | <0.0001 | 1.3796 | 0.0004 | 226.78 (<0.0001) | 86.3 | 3.9640 |
| Triglyceride (feces) | 13 | 1.4815 | <0.0001 | 1.5692 | 0.0011 | 71.66 (<0.0001) | 81.9 | 2.5666 |
| TNF-α (blood) | 14 | −1.2869 | <0.0001 | −1.3743 | 0.0026 | 96.71 (<0.0001) | 85.5 | 2.5645 |
| Body weight | 27 | −1.1740 | <0.0001 | −1.2547 | 0.0079 | 284.88 (<0.0001) | 90.5 | 5.3068 |
| Glucose (blood) | 12 | −0.7512 | <0.0001 | −0.8958 | 0.0096 | 61.64 (<0.0001) | 80.5 | 1.2356 |