γ-H2AX	histone H2AX phosphorylated on Ser139
53BP1	p53-binding protein 1
alt-NHEJ	alternative non-homologous end-joining
ASF1	anti-silencing function protein 1; histone chaperone ASF1
ASF1a	antisilencing function protein 1a; histone chaperone ASF1
ATM	ataxia telangiectasia mutated protein; serine-protein kinase ATM
ATR	ATM-and RAD-3-related kinase
BJ	human fibroblasts cell line
CAF1	chromatin assembly factor 1
CCL	chemokine (c-c motiff) ligand
Chk1	serine/threonine-protein kinase 1; checkpoint kinase 1
Chk2	serine/threonine-protein kinase 2; checkpoint kinase 2
c-NHEJ	canonical non-homologous end-joining
DDR	DNA damage response
DSB	DNA double-strand breaks
E2F	group of genes that encodes a family of transcription factors
FOXO4	forkhead box protein O4
GRO	growth-related oncogene
H2A.1	histone H2A.1
H2A.2	histone H2A.2
H2AX	variant of H3.1 histone
H3.3	histone H3.3
H3K4me2	histone H3 methylated on lysine 4
H3K56ac	histone H3 acetylated on lysine 56
H3K9ac	histone H3 acetylated on lysine 9
H3K9me	histone H3 methylated on lysine 9
H3K9me3	histone H3 triple methylated on lysine 9
HGF	hepatocyte growth factor
HIF-1	hypoxia inducible factor 1
HIRA	histone repressor A
HP1	heterochromatin protein 1
HR	homologous recombination
IGFBP	insulin-like growth factor binding protein
IL-6	interleukin 6
IL-8	interleukin 8
IMR90	Institute for Medical Research-90 cell line; human fetal lung fibroblast cell line
Ki-67	proliferation marker protein Ki-67
LMNB1	gene encoding lamin B1
MDA231	breast cancer cell line
MDC1	mediator of DNA damage checkpoint protein 1
MRC-5	fetal lung cell line
MRE11	double-strand break repair protein MRE11
MRN	MRE11/RAD50/NBS1 complex
NAD+	nicotinamide adenine dinucleotide
NFBD1	nuclear factor with BRCT domains protein 1
NF-κB	nuclear factor kappa B
NHEJ	non-homogenous end joining
p51	p51 protein
p53	p53 protein
PARP1	poly (ADP-ribose) polymerase
POT1	protection of telomeres 1
RAD17	cell cycle checkpoint protein RAD17
RAD50	RAD50 double strand break repair protein
Rap1	repressor-activator protein 1
Rb	retinoblastoma
ROS	reactive oxygen species
RPE	retinal pigment epithelium
SADS	senescence-associated distension of satelites
SAHF	senescence-associated heterochromatin foci
SASP	senescence-associated secretory phenotype
SIRT1	sirtuin 1
SIRT6	sirtuin 6
SPR-5	probable lysine-specific histone demethylase 5
TAF	telomere associated foci
TERC	telomerase RNA component
TERT	telomerase reverse transcriptase
TIN1	tunicamycin induced protein 1
TPP1	tripeptidyl peptidase 1
TRF2	telomere repeat binding factor 2
WI-38	human diploid lung fibroblasts cell line