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Immunohistochemical profile of human cutaneous Ruffini corpuscles. Immunohistochemical localization of S100 protein (a–d) in dermal Ruffini corpuscles shows different aspects depending on the section of the corpuscle, and the thickness of the capsule is also variable. (e) Surrounding the inner nucleus (S100-positive cells) of Ruffini corpuscles, there is a capsule (CD34-positive) of endoneurial nature; c: capsule; in: inner nucleus.
