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. 2021 Jan 8;26(2):282. doi: 10.3390/molecules26020282

Figure 1.

Figure 1

Biological effects on glioblastoma (GBM) tumorspheres (TSs) after combination drug administration of gossypol, phenformin, and temozolomide (TMZ) compared to control, TMZ monotherapy, and gossypol/phenformin dual therapy. (A) Cell viability and (B) ATP levels of U87 (n = 4) and TS13-64 (n = 4) were measured 72 h after combination drug therapy (mean ± SD; asterisks over each bar represent statistically significant differences compared to control; * p < 0.05, ** p < 0.01, *** p < 0.001).