Table 2.
Effect of xylitol on gastric emptying.
| A: Placebo (n = 12) |
B: Xylitol 7 g (n = 12) |
C: Xylitol 17 g (n = 12) |
D: Xylitol 35 g (n = 12) |
p-Values (Overall) |
p-Values (post-hoc) |
|
|---|---|---|---|---|---|---|
| iAUC (0–60 min) (dose × min/h) | 911 ± 129 | 917 ± 101 | 814 ± 164 | 823 ± 154 | NS | |
| iAUC (0–180 min) (dose × min/h) | 1609 ± 270 | 1733 ± 221 | 1614 ± 319 | 1767 ± 302 | NS | |
| Tmax (min) | 21.25 ± 7.7 | 21.25 ± 7.7 | 27.50 ± 5.8 | 30.00 ± 11.1 | p = 0.039 | B vs. C: p = 0.099 |
| T50% (time 50% emptied) (min) | 56.6 ± 13.0 | 65.3 ± 11.1 | 66.9 ± 13.3 | 74.0 ± 18.1 | p = 0.026 | A vs. D: p = 0.029 |
Data are expressed as mean ± SD and reported from baseline (incremental). Linear mixed-effects modeling followed by Šidak post-hoc test in case of overall.