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. 2021 Jan 10;13(2):232. doi: 10.3390/cancers13020232

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Variable response of NET, other cancers and non-cancer cell lines to TEM-induced changes in LuTate uptake. The TEM-induced changes in uptake of LuTate by NET cell lines BON-1 and NCI-H727 was compared with other cancer cell lines, such as U2OS (osteosarcoma), HeLa (cervical cancer), MCF7 (breast cancer) and H187 (small cell lung cancer), as well as with two normal cell lines NL-20 (normal bronchial epithelial), and HEK (human embryonic kidney). The cells seeded in quadruplicates were treated for 24 h with 30 µM TEM followed by recovery in fresh medium for five days. Cells were exposed for 4 h to LuTate followed by cell count and measurement of LuTate uptake per million cells, expressed as Mean ± SD.