Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
The threshold value of heteroplasmy level of mtDNA mutations in thickened intima-medial layer of carotid arteries [18,235,236,237,238,239].
| Genes | Mutations | Threshold Value of Heteroplasmy Level (%) |
|---|---|---|
| MT-TL2 | m.12315G>A | 10.4 |
| MT-RNR1 | m.652delG | 21.6 |
| MT-ND1 | m.3336T>C | 7.5 |
| MT-TL1 | m.3256C>T | 16.4 |
| MT-CYTB | m.14846G>A * | 17.4 |
| MT-RNR1 | m.652insG | 20.2 |
| MT-RNR1 | m.1555A>G * | 19.6 |
| MT-ND6 | m.14459G>A | 4.6 |
| MT-ND2 | m.5178C>A | 6.4 |
| MT-ND5 | m.13513G>A * | 33.6 |
| MT-CYTB | m.15059G>A | 26.4 |
*—Antiaherogenic mutations.
