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. 2021 Jan 12;10(1):144. doi: 10.3390/cells10010144

Figure 3.

Figure 3

Effects of gefitinib and erlotinib alone and in combination with Senexin B in parental and gefitinib- or erlotinib-adapted BT474 cells. (A–C). Effects of 7-day treatment with gefitinib (GEF) and senexin B (SNXB), alone or in 1:1 combination, in parental (A), gefitinib-adapted (B), and erlotinib-adapted (C) BT474 cells. (D–F). Effects of 7-day treatment with erlotinib (ERLO) and senexin B, alone or in 5:1 combination, in parental (D), gefitinib-adapted (E), and erlotinib-adapted (F) BT474 cells. Data shown as mean ± SEM of six replicate measurements. Combination index (CI) values at IC50 concentrations are shown in lower left corner of each graph.