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. 2021 Jan 12;10(1):144. doi: 10.3390/cells10010144

Figure 5.

Figure 5

Effects of senexin B on the development of cetuximab resistance in SW48 colon carcinoma cells. (A) Effects of 7-day treatment with the indicated concentrations of Senexin B combined with vehicle or 100 nM cetuximab on the number of live (PI-) cells relative to vehicle control and the fraction of dead (PI+) cells. (B) Effects of prolonged treatment with senexin B (1 μM), cetuximab (100 nM) or senexin B plus cetuximab combination. Cell numbers for each time point are shown relative to untreated cells (mean ± SEM of duplicate measurements; error bars at most points are smaller than symbol size).