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. 2021 Jan 12;10(1):100. doi: 10.3390/antiox10010100

Figure 1.

Figure 1

Effects of lipocalin-2 (LCN2) deficiency on hippocampal cell death in kainic acid (KA)-treated mice. (A) Cresyl violet-stained sections from KA-treated wild-type (WT) and LCN2 (−/−) mice. Arrows indicate CA3 regions that appear with pyknotic nuclei. (B) Representative immunofluorescence images (×200) of TUNEL staining (green) in hippocampal CA3 regions, counterstained with DAPI (blue). Western blot analysis and quantitative expressions of Rab5 (C) and LAMP1 (D) in the hippocampus. β-actin was used as a loading control. Data are shown as mean ± SEM. * p < 0.05 vs. WT-CTL. † p < 0.05 vs. WT + KA 6 h or WT + KA 24 h.