Figure 3.

Effect of the combined action of 3-BP and D on the viability of the PEO1, SKOV3 and MRC-5 cells. Survival of the cells treated with 3-BP at a concentration corresponding to ~half maximal inhibitory concentration (IC₅₀) (SKOV3 and MRC-5: 40 μM and PEO1: 20 μM) and various concentrations of D indicated on the axis of the abscissae (a). Plot of the combination index (CI) as a function of the effect level (Fa) for the combined action of 3-BP and D. Concentrations of 3-BP and D: 20, 40, 60 and 80 μM (b). * p < 0.05 with respect to the control (Kruskal-Wallis test; n ≥ 6).