Figure 9.

Binding efficiency on endothelial cells. HUVEC and HDMEC endothelial cells are expressing the α_vß₃ and NRP1 receptors. The binding efficiency of each type of SiNP was evaluated by flow cytometry after 30 min incubation in suspension with the cells. X-axis: Log. Fluorescence intensities. Y-axis: cell counts. Vertical dotted lines: max level of autofluorescence of the cells (green); max level of non-specific labeling with the SiNPs (black). Orange arrows indicate the presence of positively labeled cells and their size indicates the population of positively stained cells.