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. 2021 Jan 12;18(2):609. doi: 10.3390/ijerph18020609

Table 1.

Key characteristics of studies included in the systematic review.

First Author, Year Reference Study Design Country Sample Size Age (Years) Lighting Exposure Health Domain Health Outcome Main Finding Quality Score
NATURAL LIGHT
Rahayu, 2015 [28] Case-control Indonesia 212 Adults Subjective: Presence of sunlight PH OM: Tuberculosis ↑ Presence of sunlight in the house protective against tuberculosis (OR 0.06, 95% CI 0.00–0.67) * Fair
Kumar, 2001 [29] Cross-sectional India 13,320 All Subjective: Insufficient household light exposure PH OM: Leprosy ↑ Persons living in houses with insufficient sunlight exposure observed to be more afflicted by leprosy (OR 1.57, 95% CI 0.84–2.88) Fair
Brown, 2011 [30] Cross-sectional Lithuania, Switzerland, Italy, Germany, Portugal, Hungary, Slovakia and France 6017 ≥18 Subjective: Inadequate residential light PH
MH
SR: Falls and depression ↑ Participants reporting inadequate natural light in dwelling more likely to report falls (OR 1.5, 95% CI 1.2–1.9) * and depression (OR 1.4, 95% CI 1.2–1.7) * Fair
Ichimori, 2013 [31] Cross-sectional Japan 24 76–90 Objective: Daytime illuminance PH
MH
SR: Physical health and depression - No relationship between illuminance and physical health
↑ Time exposed to light over 400 lx and depression scores *
Fair
Youngstedt, 2004 [32] Cross-sectional USA 459 50–81 Objective: Morning illuminance PH
SH
SR: Mood
SR and OM: Sleep
↑ Morning illumination moderately associated with improved mood * and sleep Fair
ARTIFICIAL LIGHT
Chen, 2017 [33] Case-control Uganda 934 NR Treatment: Solar home lighting system
Comparison: Low quality sources
PH
GH
SR: Burns, cough and personal health ↑ Burns by lighting source 6.5 p.p. less; cough 9.3 p.p. less; and self-reported health 35.2 p.p. higher among households with solar home lighting system Fair
Brunnstrom, 2004 [34] Randomised trial Sweden 46 20–90 Intervention: Living room adjustment-50 Watts halogen, 12 Volt standard floor lamp GH SR: General health and depressed mood ↑ Improvement in general health p < 0.01 and depressed mood p < 0.04 after the adaptation was found for the intervention group Fair
First Author, Year Study Design Country Sample Size Age (Years) Lighting Exposure Health Domain Health Outcome Main Finding Quality Score
Falkenberg, 2019 [35] Randomised trial Norway 60 77 Intervention: Providing lamps to achieve recommended living room lighting levels (200 lux) GH SR: Visual health and general health - Self-reported visual problems and health unchanged in both groups during the intervention Good
Woldesemayat, 2014 [36] Case-control Ethiopia 1154 Adult Kerosene lamps, electricity, others PH OM: Pulmonary tuberculosis - Kerosene lamps used for lighting by 73% cases and 71.5% controls, electric lighting used by 24.5% cases and 26.6% controls. The remaining participants used other kerosene-based or other light sources Fair
Savitha, 2007 [37] Case-control India 208 0–5 Kerosene lamps, electricity PH OM: Acute lower respiratory infection (ALRI) ↑ 36.54% of ALRI cases used kerosene lamps for lighting compared to 2.88% of controls, which used electric lighting Fair
Patel, 2019 [27] Cross-sectional India 932,341 0–59 months Electricity and solar, kerosene and other oils, others PH SR: Acute respiratory infection (ARI) ↑ Kerosene and other sources for lighting have higher (OR 1.07, 95% CI 1.05–1.10) * for ARI compared to electric and solar lighting Fair
Mashreky, 2010 [38] Case–control Bangladesh 840 <10 Use of traditional kerosene lamp (kupi bati) PH OM: Burn ↑ Using a kupi bati increased risk of burn (OR 3.16, 95% CI 1.58–6.35) * with attributable risk of 68.38% Fair
Camilloni, 2011 [39] Case-control Italy 74 65–85 Subjective: Poor lighting PH SR: Home injuries ↑ Poor household illumination associated with home injuries (OR 3.00, 95% CI 1.41–6.38) * Fair
Shi, 2014 [40] Cross-sectional China 472 Adults Subjective: Sufficient lighting for stairway PH SR: Falls ↑ Sufficient lighting for stairway can lower the risk for a single fall (OR 0.45, 95% CI 0.21–0.96) * Good
Isberner, 1998 [41] Case-control USA 90 ≥60 Subjective: Poor lighting at stairs PH SR: Falls ↑ Participants with poor lighting at stairs had a higher chance of falling (OR 3.31, 95% CI 0.63–17.36) Fair
First Author, Year Study Design Country Sample Size Age (Years) Lighting Exposure Health Domain Health Outcome Main Finding Quality Score
Czepita, 2004 [42] Cross-sectional Poland 3636 6–18 Type of lighting: Fluorescent or incandescent in living room, dining room, child’s room, parent’s room, kitchen and bathroom. PH OM: Refractive error: emmetropia, myopia, hyperopia, astigmatism and anisometropia ↑ Higher prevalence of hyperopia with fluorescent lamp in kitchen (p < 0.01) *
- No statistically significant findings for other exposure-outcome combinations
Fair
Hopkins, 2017 [43] Crossover UK 80 >60 Blue-enriched white lighting (17,000 K ≃ 900 lux), white lighting (4000 K ≃200 lux) MH
SH
SR: Mood
SR and OM: Sleep
↑ Blue-enriched lighting reduced anxiety, sleep efficiency and quality *
↑ Blue-enriched light increased night-time activity *
Fair
Kayaba, 2014 [44] Cross-sectional Japan 351 20–70 Light-emitting diode (LED), light bulb, fluorescent light SH SR: Sleep quality Compared with LED lighting:
↑ Light bulbs (OR: 3.7, 95% CI 1.1–12.6) * were risk factors for variable sleep quality
- Fluorescent lighting produced no significant results (OR 2.1, 95% CI 0.8–5.7)
Fair
LIGHT AT NIGHT
Czepita, 2004 [42] Cross-sectional Poland 3636 6–18 Lighting habit: Sleeping in darkness or with the light on PH OM: Refractive error (emmetropia, myopia, hyperopia, astigmatism and anisometropia) - No relationship between prevalence of refractive error and sleeping with the light turned on or off at night Fair
O’Leary, 2006 [45] Case-control USA 1161 <75 Lighting habit during sleep hours PH OM: Breast cancer ↑ Increased risk of breast cancer for women who frequently turned on lights at home during sleep hours (OR 1.65, 95% CI 1.02–2.69) * Fair
First Author, Year Study Design Country Sample Size Age (Years) Lighting Exposure Health Domain Health Outcome Main Finding Quality Score
Obayashi, 2015 [46] Cross-sectional Japan 700 ≥60 Objective: Indoor illumination level PH OM: Carotid atherosclerosis ↑ With each quartile increase in light exposure, mean carotid intima-media thickness increased (ptrend = 0.002) * Good
Obayashi, 2013 [47] Cross-sectional Japan 528 ≥60 Objective: Indoor illumination level PH SR and OM: Obesity and dyslipidaemia ↑ Light intensity and Body Mass Index (OR 1.89, 95% CI 1.02–2.57) *; abdominal obesity (OR 1.62, 95% CI 1.02–2.57) *; and dyslipidaemia (OR 1.72, 95% CI 1.11–2.68) * Good
Obayashi, 2014 [48] Cross-sectional Japan 528 ≥60 Objective: Indoor illumination level PH OM: Night-time blood pressure ↑ Light intensity (≥5 lux) higher night-time systolic BP (adjusted mean: 120.8 vs. 116.5 mmHg) and diastolic BP (70.1 vs. 67.1 mmHg) compared with group <5lux Good
Obayashi, 2014 [49] Cross-sectional Japan 513 ≥60 Objective: Indoor illumination level PH OM: Diabetes ↑ Brighter evening light amounts and increase in diabetes prevalence (OR 1.72, 95% CI 1.12–2.64) * Good
Yamauchi, 2014 [50] Crossover Japan 17 Adult Light environment:
1000 lux, Dark: 0 lux
PH
SH
SR and OM: Sleep (efficacy, latency and apnea) and
heart rate variability
↑ Higher low-frequency power divided by high-frequency ratio power in the analysis of heart rate variability and apnea-hypopnea index in the light environment *
- No other differences in sleep in the different light environments
Fair
Obayashi, 2013 [51] Cross-sectional Japan 516 ≥60 Objective: Indoor illumination level MH SR: Depression Higher prevalence of light intensity ≥5lux in the depressed group compared with that in the nondepressed group (OR 1.89, 95% CI 1.10–3.25) *
↑ Light at night 10 lux ≥30 min is a risk for depressive symptoms (OR 1.71, 95% CI 1.01–2.89) *
Good
Obayashi, 2018 [52] Longitudinal Japan 863 ≥60 Objective: Indoor illumination level MH SR: Depression ↑ Light intensity (≥5 Lux) and higher depression risk (HR 1.78, 95% CI 1.07–2.96) * Good
Obayashi, 2014 [53] Cross-sectional Japan 857 ≥60 Objective: Indoor illumination level SH SR and OM: Sleep quality Highest quartile of light intensity showed higher odds for insomnia (OR 1.61, 95% CI 1.05–2.45) *; higher OR for insomnia with each quartile increase in light exposure (ptrend = 0.043) * Good
Obayashi, 2014 [54] Longitudinal Japan 192 ≥60 Objective: Indoor illumination level SH OM: Sleep onset latency ↑ Brighter evening light amounts and longer sleep onset latency (regression co-efficient 0.133, 95% CI 0.020–0.247) * Good

Abbreviations: PH = physical health, MH = mental health, SH = sleep health, GH = general health, OM = objectively measured, SR = self-reported, NR = not reported, OR = odds ratio, HR = hazard ratio, p.p = percentage points, = expected direction of association, ↓ = unexpected direction of association, - = no association * = statistically significant with p < 0.05.