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. 2021 Jan 13;10(1):146. doi: 10.3390/cells10010146

Figure 5.

Figure 5

Pharmacological activation of β2-ARs leads to mitochondrial fusion in skeletal muscle. Mitochondrial area (a), perimeter (b), elongation (c), mitochondria number per area (d), and electron microscopy representative images (e) of tibialis anterior muscle from mice treated with the non-selective β-AR agonist isoproterenol (ISO—single dose—10 mg/kg, i.p. 30 min), with or without β2-AR receptor blockade with ICI 118,551 (single dose—10 mg/kg, i.p., 30 min prior to ISO treatment). Data are presented as mean ± SE. * p < 0.05 vs. control and ** p < 0.05 vs. ISO. n = 5/group.