Table 1.
The histomorphometrical parameters of the duodenum and jejunum in male Wistar rats in the CONT (sham-operated) and GASTR (subjected to gastrectomy) groups.
| Parameter | Duodenum | Jejunum | ||
|---|---|---|---|---|
| CONT | GAST | CONT | GAST | |
| Myenteron longitudinal lamina thickness, μm | 34.4 ± 8.85 | 29.2 ± 6.06 | 15.7 ± 4.6 | 27.2 ± 3.0 *** |
| Myenteron transversal lamina thickness, μm | 52.5 ± 12.1 | 46.0 ± 9.1 | 22.7 ± 3.7 | 40.7 ± 3.7 *** |
| Submucosa thickness, μm | 40.3 ± 8.2 | 25.4 ± 7.8 ** | 15.4 ± 7.6 | 31.7 ± 5.3 ** |
| Mucosa thickness, μm | 885 ± 73 | 825 ± 68 | 723 ± 31 | 825 ± 68 ** |
| Villus length, µm | 628 ± 34 | 622 ± 53 | 492 ± 59 | 460 ± 43 |
| Villus thickness, µm | 81.4 ± 10.3 | 81.8 ± 7.8 | 76.0 ± 9.8 | 81.3 ± 13.5 |
| Total number of villi, /mm | 9.1 ± 1.5 | 8.4 ± 0.8 | 9.9 ± 0.9 | 9.1 ± 1.0 |
| Villus epithelium thickness, µm | 30.9 ± 4.7 | 31.7 ± 4.4 | 28.9 ± 5.5 | 31.0 ± 6.7 |
| Enterocyte number, /100 µm of villus | 13.5 ± 1.4 | 14.8 ± 1.4 | 16.2 ± 1.9 | 13.5 ± 1.8* |
| Total crypts number, /mm | 13.2 ± 2.7 | 11.6 ± 1.6 | 16.9 ± 3.9 | 17.3 ± 3.3 |
| Active crypts number, /mm | 4.4 ± 1.5 | 2.6 ± 0.7 * | 5.7 ± 1.2 | 5.4 ± 1.9 |
| Inactive crypts number, /mm | 8.8 ± 2.6 | 9.0 ± 1.7 | 10.3 ± 3.8 | 11.9 ± 4.0 |
| Crypt depth, μm | 168 ± 27 | 146 ± 30 | 148 ± 19 | 136 ± 17 |
| Crypt width, µm | 52.7 ± 9.1 | 55.3 ± 8.6 | 44.3 ± 10.4 | 47.1 ± 9.0 |
| Intestine absorptive surface, µm2 | 4.2 ± 0.6 | 4.9 ± 1.0 | 3.9 ± 0.6 | 4.0 ± 0.5 |
| Immature collagen, % | 4.1 ± 2.2 | 7.6 ± 2.4 * | 3.5 ± 1.5 | 10.8 ± 2.6 *** |
| Ki index | 0.61 ± 0.06 | 0.68 ± 0.06 | 0.39 ± 0.13 | 0.56 ± 0.07 * |
| Ki number, /0.01 mm2 of the gland surface | 9.08 ± 2.01 | 8.11 ± 1.08 | 6.6 ± 1.8 | 10.1 ± 2.8 * |
Table shows mean ± standard deviation. Statistical significance: * p < 0.05; ** p < 0.01; *** p < 0.001. Significance was established using a two-tailed Student’s t-test (normally distributed data), Welch’s test (normally distributed data with unequal variances) or the Mann–Whitney test (for pairwise comparisons with at least one non-normally distributed dataset). Ki index—the number of proliferating cells in relation to all gland cells; Ki number—the number of proliferating cells.