ALS |
Amyotrophic lateral sclerosis |
AMBRA1 |
Autophagy and beclin 1 regulator 1 |
AMPK |
AMP-activated protein kinase |
ATP |
Adenosine triphosphate |
CCCP |
Carbonyl cyanide m-chlorophenyl hydrazone |
CNS |
Central nervous system |
CS |
Citrate synthase |
DAMPs |
Damage-associated molecular patterns |
fALS |
Familiar ALS |
FF motoneuron |
Fast fatigable motoneuron |
FR motoneuron |
Fast resistant motoneuron |
FUNDC1 |
FUN14 domain containing protein 1 |
FUS
|
Fused in sarcoma |
GABARAPL1 |
Gamma-aminobutyric acid receptor-associated protein-like 1 |
IFN |
Interferon type I |
ISG |
Interferon-stimulated genes |
IRF3 |
Interferon regulatory factor 3 |
LAP |
LC3-associated phagocytosis |
LC3 |
Microtubule-associated proteins 1A/1B light chain 3B |
LIR |
LC3-interaction region |
MARCH5 |
Membrane-associated ring finger 5 ubiquitin-ligase |
MFN1 |
Mitofusin 1 |
MFN2 |
Mitofusin 2 |
MIRO1 |
Mitochondrial Rho GTPase 1 |
mTORC1 |
Mammalian target of rapamycin complex 1 |
MULAN |
Mitochondrial ubiquitin-ligase activator of NF-kB |
NBR1 |
Neighbor of BRCA1 gene 1 |
NDP52 |
Nuclear dot protein 52 |
NF-kB |
Nuclear factor-kappa B |
NMJ |
Neuromuscular junction |
OPTN
|
Optineurin |
P2X7 |
P2X purinoceptor 7 |
PGC-1α |
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha |
PINK1 |
PTEN-induced kinase 1 |
RLPK1 |
Receptor-like protein kinase 1 |
ROS |
Reactive oxygen species |
sALS |
Sporadic ALS |
SMCR8 |
Smith-Magenis syndrome chromosome region candidate 8 |
SOD1
|
Superoxide dismutase 1 |
TAX1BP1 |
TAX1 binding protein |
TBK1
|
TANK-binding kinase 1 |
TDP-43 |
43 kDa transactive response DNA binding protein |
TFAM |
Mitochondrial transcription factor A |
TIM |
Translocase of the inner membrane |
TLR3 |
Toll-like receptor 3 |
TOM |
Translocase of the outer membrane |
ULK1 |
Unc-51 like autophagy activating kinase 1 |
UPS |
Ubiquitin-proteasome system |
VDAC1 |
Voltage-dependent anion channel 1 |