Figure 2.

Ginger supplementation ameliorated HF-diet-induced metabolic parameters without a change in food intake. Male 6-week-old C57BL/6 mice were fed an LF (white circle, white bar), HF (black triangle, black bar), or HF + G (gray square, gray bar) diet for 7 weeks (n = 4–5 per group). (A) body weight (g); (B) body weight (%) AUC (BW gain throughout the 7 weeks experiment expressed as % change from week 0 with AUC); (C) food intake (g/day); (D) feeding efficiency ratio (FER, %), calculated as body weight gain (g/day) divided by food intake (g/day); (E) fasting glucose levels (mg/dL); and (F) fasting serum total cholesterol levels (mg/dL). Data are expressed as the mean ± SEM (n = 4–5). n.s. represents no significance. Bars with different letters are significantly different according to one-way ANOVA with Bonferroni’s comparison test; * p < 0.05, ** p < 0.01, *** p < 0.001 (LF vs. HF); ^# p < 0.05, ^## p < 0.01 (HF vs. HF + G).