Fig. 1:

Four examples of breasts that were biopsied along with the annotated findings. The breasts (from left to right) were diagnosed with benign calcifications, a benign mass, malignant calcifications, and malignant architectural distortion. While microcalcifications are common in both benign and malignant findings, their presence in a ductal distribution, such as in the third example, is a strong indicator of malignancy.