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. 2021 Jan 14;13(1):219. doi: 10.3390/nu13010219

Table 4.

Logistic regression analysis to examine the effect modification by the comorbidity burden on the effectiveness of vitamin D on the study outcome.

Comorbidity Burden Crude Effect Modification Analysis * (OR, 95% CI and p-Value) Adjusted Effect Modification Analysis ** (OR, 95% CI and p-Value)
0 3.26 (0.48–22.2) 3.59 (0.52–24.8)
1 1.16 (0.36–3.76) 1.32 (0.39–4.43)
2 0.41 (0.16–1.05) 0.49 (0.18–1.32)
≥3 0.15 (0.034–0.64) 0.18 (0.04–0.83)
P for effect modification by comorbidity burden 0.033 0.039

* Adjusted for the main effect of vitamin D treatment and comorbidity burden. ** Adjusted for the main effect of vitamin D treatment, comorbidity burden and propensity score 2. OR = odds ratio, CI = confidence interval. p-value < 0.05 in bold.