Table 4.
Logistic regression analysis to examine the effect modification by the comorbidity burden on the effectiveness of vitamin D on the study outcome.
| Comorbidity Burden | Crude Effect Modification Analysis * (OR, 95% CI and p-Value) | Adjusted Effect Modification Analysis ** (OR, 95% CI and p-Value) |
|---|---|---|
| 0 | 3.26 (0.48–22.2) | 3.59 (0.52–24.8) |
| 1 | 1.16 (0.36–3.76) | 1.32 (0.39–4.43) |
| 2 | 0.41 (0.16–1.05) | 0.49 (0.18–1.32) |
| ≥3 | 0.15 (0.034–0.64) | 0.18 (0.04–0.83) |
| P for effect modification by comorbidity burden | 0.033 | 0.039 |
* Adjusted for the main effect of vitamin D treatment and comorbidity burden. ** Adjusted for the main effect of vitamin D treatment, comorbidity burden and propensity score 2. OR = odds ratio, CI = confidence interval. p-value < 0.05 in bold.