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. 2021 Jan 14;11(1):54. doi: 10.3390/life11010054

Figure 1.

Figure 1

Synthetic torpor induced by GABA-A agonist muscimol. (A) In an animal exposed to constant darkness at an ambient temperature of 15 °C, repeated injections of muscimol in the rostral ventromedial medulla (RVMM, the black arrows at the top) induced a suspended animation state characterized by a reduced deep brain temperature (Tbrain), heart rate (HR), and electroencephalogram (EEG) voltage, as well as a shift of the EEG power spectrum. No significant changes in arterial pressure (AP) were observed. Infrared images at the bottom show the state of cutaneous vasomotion (B) in the pre-injection period, (C) following the first injection of muscimol in the RVMM, and (D) at end of treatment. This was adapted from [19]. Copyright 2013, Society for Neuroscience.