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. 2020 Aug 4;192(31):E875–E891. doi: 10.1503/cmaj.191707

Table 2:

Summary of guideline development process

Activity Responsible group
• Mind-mapping exercise to identify the scope of the guideline and the broad sections and chapters (19 chapters) Executive committee
• Develop research questions (PICO[T]) for each chapter Steering committee
• Conduct literature search77 MERST
• Load results of the literature search into the Distiller Systematic Review software program MERST
• Conduct critical appraisal of all papers77 Chapter leads
• Review results of critical appraisal and assign evidence grades to each paper using AGREE II tool78 MERST
• Develop reports with graded evidence MERST
• Develop recommendations based on the highest level of evidence and expert consensus Steering Committee with chapter leads and authors
• Review recommendations to ensure fidelity with the evidence (only for recommendations using grade A–C level evidence) MERST
• Review recommendations to ensure fidelity with the evidence and relevance to primary care health care professionals Executive committee
• Revise recommendations based on feedback from the executive committee and MERST Steering committee with chapter leads
• Review and approve final recommendations Executive committee
• External review of recommendations to assess relevance and feasibility Family physicians and people living with obesity
• External peer review of chapters Experts in each area

Note: AGREE = Appraisal of Guidelines for Research and Evaluation, MERST = McMaster Evidence Review and Synthesis Team; PICO(T) = Population, Intervention, Comparison, Outcome, Time.