Table 3.
Correlation values between healthy controls and patients with OCD
| Region | Healthy controls (n = 41) | OCD (n = 49) | 2-sample t test direction | p value* |
|---|---|---|---|---|
| Inter-iFC | ||||
| rFPN–DMN | 0.27 | 0.28 | 0.76 | |
| rFPN–IFPN | 0.49 | 0.33 | Healthy controls > OCD | < 0.001‡ |
| rFPN–SN | 0.25 | 0.23 | 0.76 | |
| DMN–IFPN | 0.15 | 0.14 | 0.75 | |
| DMN–SN | −0.02 | −0.01 | 0.76 | |
| IFPN–SN | 0.21 | 0.13 | 0.08 | |
| Sliding time window† | ||||
| rFPN–DMN | 0.71 | 0.77 | 0.30 | |
| rFPN–IFPN | 1.01 | 0.80 | Healthy controls > OCD | < 0.001‡ |
| rFPN–SN | 0.74 | 0.71 | 0.65 | |
| DMN–IFPN | 0.59 | 0.59 | 0.92 | |
| DMN–SN | 0.44 | 0.45 | 0.88 | |
| IFPN–SN | 0.73 | 0.55 | Healthy controls > OCD | 0.007‡ |
DMN = default mode network; iFC = intrinsic functional connectivity; lFPN = left frontoparietal network; OCD = obsessive–compulsive disorder; rFPN = right frontoparietal network; SN = salience network.
*
From 2-sample t tests reduced to p > 0.0083 after Bonferroni correction for 6 t tests
†
Fisher z-transformed mean peak correlation values between healthy controls and patients with OCD.
‡
Significant at p < 0.05.