TABLE II.
Characteristics of most recent reaction of FARE Registry respondents
| Parent/guardian respondent |
Self-respondent |
Total |
|||||||
|---|---|---|---|---|---|---|---|---|---|
| N | % | 95% CI | N | % | 95% CI | N | % | 95% CI | |
| All respondents reporting reaction | 1847 | 1207 | 3054 | ||||||
| Context of reaction | |||||||||
| Accidental | 1463 | 79.2 | (77.3-81.0) | 1044 | 86.5 | (84.4-88.3) | 2507 | 82.1 | (80.7-83.4) |
| Nonaccidental (intentional) | 188 | 10.2 | (8.9-11.6) | 113 | 9.4 | (7.8-11.1) | 301 | 9.9 | (8.8-11.0) |
| Medical care related | 130 | 7.0 | (6.0-8.3) | 16 | 1.3 | (0.8-2.2) | 146 | 4.8 | (4.1-5.6) |
| Unsure | 66 | 3.6 | (2.8-4.5) | 34 | 2.8 | (2.0-3.9) | 100 | 3.3 | (2.7-4.0) |
| Age in years at time of reaction | 1847 | 1207 | 3054 | ||||||
| <5 | 982 | 53.2 | (50.9-55.4) | 67 | 5.6 | (4.4-7.0) | 1049 | 34.3 | (32.7-36.1) |
| 5-12 | 662 | 35.8 | (33.7-38.1) | 28 | 2.3 | (1.6-3.3) | 690 | 22.6 | (21.1-24.1) |
| 13-17 | 193 | 10.4 | (9.1-11.9) | 55 | 4.6 | (3.5-5.9) | 248 | 8.1 | (7.2-9.1) |
| 18-25 | 10 | 0.5 | (0.3-1.0) | 245 | 20.3 | (18.1-22.7) | 255 | 8.3 | (7.4-9.4) |
| 26-66 | 0 | 0.0 | (0.0-0.0) | 764 | 63.3 | (60.5-66.0) | 764 | 25.0 | (23.5-26.6) |
| >66 | 0 | 0.0 | (0.0-0.0) | 48 | 4.0 | (3.0-5.2) | 48 | 1.6 | (1.2-2.1) |
| Type of food allergen | |||||||||
| Peanut | 506 | 27.4 | (25.4-29.5) | 160 | 13.3 | (11.5-15.3) | 666 | 21.8 | (20.4-23.3) |
| Treenut | 308 | 16.7 | (15.0-18.4) | 191 | 15.8 | (13.9-18.0) | 499 | 16.3 | (15.1-17.7) |
| Egg | 219 | 11.9 | (10.5-13.4) | 54 | 4.5 | (3.4-5.8) | 273 | 8.9 | (8.0-10.0) |
| Milk | 253 | 13.7 | (12.2-15.3) | 107 | 8.9 | (7.4-10.6) | 360 | 11.8 | (10.7-13.0) |
| Shellfish | 23 | 1.2 | (0.8-1.9) | 83 | 6.9 | (5.6-8.4) | 106 | 3.5 | (2.9-4.2) |
| Fin fish | 22 | 1.2 | (0.8-1.8) | 20 | 1.7 | (1.1-2.6) | 42 | 1.4 | (1.0-1.9) |
| Wheat | 42 | 2.3 | (1.7-3.1) | 76 | 6.3 | (5.1-7.8) | 118 | 3.9 | (3.2-4.6) |
| Soy | 16 | 0.9 | (0.5-1.4) | 39 | 3.2 | (2.4-4.4) | 55 | 1.8 | (1.4-2.3) |
| Sesame | 53 | 2.9 | (2.2-3.7) | 31 | 2.6 | (1.8-3.6) | 84 | 2.8 | (2.2-3.4) |
| Beans | 35 | 1.9 | (1.4-2.6) | 11 | 0.9 | (0.5-1.6) | 46 | 1.5 | (1.1-2.0) |
| Cereals | 4 | 0.2 | (0.1-0.6) | 17 | 1.4 | (0.9-2.3) | 21 | 0.7 | (0.4-1.1) |
| Seeds (other than mustard, sesame) | 27 | 1.5 | (1.0-2.1) | 10 | 0.8 | (0.4-1.5) | 37 | 1.2 | (0.9-1.7) |
| Mustard | 5 | 0.3 | (0.1-0.6) | 7 | 0.6 | (0.3-1.2) | 12 | 0.4 | (0.2-0.7) |
| Meats | 8 | 0.4 | (0.2-0.9) | 35 | 2.9 | (2.1-4.0) | 43 | 1.4 | (1.0-1.9) |
| Herbs or spices | 4 | 0.2 | (0.1-0.6) | 28 | 2.3 | (1.6-3.3) | 32 | 1.0 | (0.7-1.5) |
| Fruits or vegetables | 54 | 2.9 | (2.2-3.8) | 98 | 8.1 | (6.7-9.8) | 152 | 5.0 | (4.3-5.8) |
| Other/unsure/missing | 268 | 14.5 | (13.0-16.2) | 240 | 19.9 | (17.7-22.2) | 508 | 16.6 | (15.4-18.0) |
| Processed or prepackaged food | |||||||||
| Yes | 954 | 51.7 | (49.4-53.9) | 467 | 38.7 | (36.0-41.5) | 1421 | 46.5 | (44.8-48.3) |
| No | 709 | 38.4 | (36.2-40.6) | 551 | 45.7 | (42.9-48.5) | 1260 | 41.3 | (39.5-43.0) |
| Unsure | 181 | 9.8 | (8.5-11.2) | 185 | 15.3 | (13.4-17.5) | 366 | 12.0 | (10.9-13.2) |
| Unspecified/missing | 3 | 0.2 | (0.1-0.5) | 4 | 0.3 | (0.1-0.9) | 7 | 0.2 | (0.1-0.5) |
| Self-perceived severity of reaction | |||||||||
| Mild | 467 | 25.3 | (23.4-27.3) | 315 | 26.1 | (23.7-28.7) | 782 | 25.6 | (24.1-27.2) |
| Moderate | 630 | 34.1 | (32.0-36.3) | 439 | 36.4 | (33.7-39.1) | 1069 | 35.0 | (33.3-36.7) |
| Severe | 499 | 27.0 | (25.0-29.1) | 286 | 23.7 | (21.4-26.2) | 785 | 25.7 | (24.2-27.3) |
| Very severe | 236 | 12.8 | (11.3-14.4) | 154 | 12.8 | (11.0-14.8) | 390 | 12.8 | (11.6-14.0) |
| Unsure | 15 | 0.8 | (0.5-1.3) | 13 | 1.1 | (0.6-1.8) | 28 | 0.9 | (0.6-1.3) |
| Place of exposure (excluding medical cause of exposure) | |||||||||
| Home | 856 | 49.9 | (47.5-52.2) | 408 | 34.3 | (31.6-37.0) | 1264 | 43.5 | (41.7-45.3) |
| Outside of home | 861 | 50.1 | (47.8-52.5) | 783 | 65.7 | (63.0-68.4) | 1644 | 56.5 | (54.7-58.3) |
| Treatment type | |||||||||
| None | 251 | 13.6 | (12.1-15.2) | 194 | 16.1 | (14.1-18.3) | 445 | 14.6 | (13.4-15.9) |
| Type 1 or 2 antihistamines | 1319 | 71.4 | (69.3-73.4) | 825 | 68.4 | (65.7-70.9) | 2144 | 70.2 | (68.6-71.8) |
| Type 1 antihistamines | 1288 | 69.7 | (67.6-71.8) | 810 | 67.1 | (64.4-69.7) | 2098 | 68.7 | (67.0-70.3) |
| Type 2 antihistamines | 211 | 11.4 | (10.1-13.0) | 137 | 11.4 | (9.7-13.3) | 348 | 11.4 | (10.3-12.6) |
| EPI autoinjector | 426 | 23.1 | (21.2-25.0) | 270 | 22.4 | (20.1-24.8) | 696 | 22.8 | (21.3-24.3) |
| EPI (IV) | 194 | 10.5 | (9.2-12.0) | 107 | 8.9 | (7.4-10.6) | 301 | 9.9 | (8.8-11.0) |
| Oral corticosteroids | 350 | 18.9 | (17.2-20.8) | 188 | 15.6 | (13.6-17.7) | 538 | 17.6 | (16.3-19.0) |
| Topical corticosteroids | 102 | 5.5 | (4.6-6.7) | 64 | 5.3 | (4.2-6.7) | 166 | 5.4 | (4.7-6.3) |
| Bronchodilator | 257 | 13.9 | (12.4-15.6) | 146 | 12.1 | (10.4-14.1) | 403 | 13.2 | (12.0-14.4) |
| IV fluids | 166 | 9.0 | (7.8-10.4) | 103 | 8.5 | (7.1-10.2) | 269 | 8.8 | (7.9-9.9) |
| Oxygen therapy | 80 | 4.3 | (3.5-5.4) | 51 | 4.2 | (3.2-5.5) | 131 | 4.3 | (3.6-5.1) |
| Atropine | 6 | 0.3 | (0.1-0.7) | 3 | 0.2 | (0.1-0.8) | 9 | 0.3 | (0.2-0.6) |
| Glucagon | 2 | 0.1 | (0.0-0.4) | 0 | 0.0 | (0.0-0.0) | 2 | 0.1 | (0.0-0.3) |
| Unsure | 34 | 1.8 | (1.3-2.6) | 24 | 2.0 | (1.3-2.9) | 58 | 1.9 | (1.5-2.4) |
| Other | 143 | 7.7 | (6.6-9.1) | 103 | 8.5 | (7.1-10.2) | 246 | 8.1 | (7.1-9.1) |
CI, Confidence interval; FARE, Food Allergy Research and Education; IV, intravenous.
All respondents were asked about their age and context at the time of their reaction (unintentional, intentional, medical care related, unsure). Additional information was captured by asking questions about processed or prepackaged food, self-perceived severity of reaction, place of exposure, and treatment type.