Figure 2.

Neutrophil functions. To combat infection, neutrophils can execute various functions. Phagocytosis is the uptake of pathogens inside the cell. NETosis is a form of cell death in which neutrophils expulse their DNA together with histones and granular proteins (neutrophil extracellular traps). During degranulation, neutrophils release enzymes and antibacterial peptides which are normally stored inside granules. During the release of reactive oxygen species, neutrophils convert oxygen to highly reactive forms that are capable of damaging pathogens. Finally, neutrophils release cytokines, activating other immune cells and attracting them to the site of infection.