Table 1.

Functions Which Differentiated HL-60 Cells are Capable of Executing

Function	Stimulus	Differentiation Agent	References
Cell polarization	fMLF	DMSO, DMF	[80,86]
	CXCL8	ATRA, DMSO	[86]
Chemotaxis	fMLF	DMSO, dbcAMP	[81,86,87]
	CXCL8	ATRA, DMSO	[86]
	LTB4	RA	[87]
	C5a	dbcAMP	[88]
ROS production	PMA	DMSO, ATRA	[126,127]
	fMLF	DMSO	[126]
	Opsonized zymosan	DMSO	[127]
NETosis	CIs	DMSO, ATRA, DMF	[134,141–143]
	PMA	ATRA, DMF	[142,143]
Phagocytosis	Saccharomyces Cerevisiae	RA	[146]
	Latex beads	DMSO, RA	[87]
	Antibody-coated bacteria	DMF	[114,115,147]
	Complement-coated bacteria	DMF	[148]

Abbreviations: ATRA, all-trans retinoic acid; C5a, complement component 5a; CIs, calcium ionophores; CXCL8, CXC motif chemokine ligand 8; dbcAMP, dibutyryl cyclic AMP; DMF, dimethylformamide; DMSO, dimethyl sulfoxide; fMLF, N-formyl-methionine-leucyl-phenylalanine; LTB4, leukotriene B4; PMA, phorbol 12-myristate 13-acetate; RA, retinoic acid; ROS, reactive oxygen species.