Table 3.
Expression of Phagocytic Receptors on Undifferentiated (uHL-60) and Differentiated (dHL-60) Cells
| Receptor | Examples of Ligands | Expression on uHL-60 | Expression on dHL-60 | References |
|---|---|---|---|---|
| C1qRp | C1q?a | - | DMSO: - or + RA: - |
[101,102] |
| CR1 (CD35) | C1q, C3b, C4b, MBL | - | DMSO: ++ RA: ++ |
[103–105] |
| CR3 (CD11b/CD18) | iC3b | + | DMSO: ++ RA: ++ |
[82,101,102,104,106] |
| CR4 (CD11c/CD18) | iC3b | - | DMSO: + RA: + |
[85] |
| FcγRI | IgG1, IgG3, IgG4, IgG immune complexes | + or ++ | DMSO: ++ ATRA: ++ DMF: ++ |
[107–109] |
| FcγRII | IgG immune complexes | + or ++ | RA: ++ | [107,108,110] |
| FcγRIII | IgG3, IgG immune complexes | - | unknown | [107,108] |
Note: aThe question mark indicates that the affinity of C1qRp for C1q is still under debate.
Abbreviations: ATRA, all-trans retinoic acid; C1q, complement component 1q; C1qRp, C1q receptor; C3b, complement component 3b; C4b, complement component 4b; CR, complement receptor; DMF, dimethylformamide; DMSO, dimethyl sulfoxide; FcγR, Fcγ receptor; IgG, immunoglobulin G; RA, retinoic acid; -, no expression; +, low expression; ++, moderate to high expression.