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. 2021 Jan 21;7(1):e06027. doi: 10.1016/j.heliyon.2021.e06027

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© 2021 The Author(s)

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

The effect of glyphosate exposure on microtubule stability. Microtubule dynamics are vital to developmental processes, and these dynamics are kept in equilibrium by several mechanisms that involve post-translational modifications (α-tubulin acetylation) and microtubule-associated proteins (MAPs). Glyphosate exposure during embryonic development in zebrafish can result in a reduction of the levels of acetylated α-tubulin and a loss of microtubule stability without generating any apparent changes in the stability of actin filaments, suggesting that glyphosate can modify the function of the cytoskeleton by altering microtubule stability. Created with BioRender.com.