Table 7.
Combined effect estimates and heterogeneity for actigraphy outcomes between dementia and control samples.
| Actigraphy measure | Included studies, no. | Dementia subjects, no. | Healthy subjects, no. | Pooled mean difference, random-effects model (95% CI) | Q | I2 (95% CI) |
|---|---|---|---|---|---|---|
| IS | 10 | 298 | 180 | −0.47 (−0.81, −0.14)† | 24.86 (9 df)§ | 64 (29, 82) |
| IV | 9 | 245 | 171 | 0.46 (0.27, 0.65)† | 6.61 (8 df) | 0 (0, 65) |
| RA | 9 | 237 | 152 | −0.53 (−0.76, −0.30)† | 15.39 (8 df) | 48 (0, 76) |
| L5 | 8 | 184 | 103 | 0.38 (0.15, 0.61)§ | 11.21 (7 df) | 38 (0, 72) |
| M10 | 8 | 184 | 103 | −0.61 (−1.16, −0.06)§ | 30.32 (7 df)† | 77 (54, 88) |
| TST | 7 | 291 | 212 | 0.46 (−0.21, 1.12) | 30.31 (6 df)† | 80 (60, 90) |
| SE | 8 | 193 | 171 | −0.52 (−0.89, −0.16)§ | 15.44 (7 df)§ | 55 (0, 80) |
| Amplitude | 7 | 174 | 93 | −1.22 (−1.94, −0.50)‡ | 36.34 (6 df)† | 83 (67, 92) |
| Daytime Activity | 7 | 210 | 136 | −1.60 (−2.66, −0.55)§ | 81.82 (6 df)† | 93 (87, 96) |
df, degrees of freedom; IS, interdaily stability; IV, intradaily variability; I2, percentage of variation across studies due to heterogeneity; L5, activity of least active 5 h; M10, activity of most active 10 h; No., number; Q, Cochran's Q weighted sum of squares of effect size estimates subtracted by their mean; RA, relative amplitude; SE, sleep efficiency; TST, total sleep time.
†
p < 0.0001.
‡
p < 0.001.
§
p < 0.05.