Table 3.
Comparison of oral health-related quality of life of oral squamous cell carcinoma survivors among study groups at 1-month and 6-months of post-treatment.
| OHIP-14 | Study groups | N (135) | 1-month post-treatment |
6-months post-treatment |
Comparison between 1-month and 6-months post-treatment | ||||
|---|---|---|---|---|---|---|---|---|---|
| Mean | SD | p value | Mean | SD | p value | ||||
| FL | Surgery (A) | 45 | 2.64 | 0.60 | A < B < C (p < 0.001) | 0.60 | 0.61 | A < B < C (p < 0.001) | P < 0.001 |
| Post-surgical RT (B) | 45 | 3.51 | 0.50 | 1.68 | 0.70 | P < 0.001 | |||
| Post-surgical CRT (C) | 45 | 4.00 | 0.00 | 2.82 | 0.44 | P < 0.001 | |||
| Total | 135 | 3.37 | 0.72 | 1.70 | 1.07 | P < 0.001 | |||
| PP | Surgery (A) | 45 | 2.48 | 0.75 | A < B, A < C (p < 0.001); B < C (p = 0.011) |
0.60 | 0.57 | A < B < C (p < 0.001) | P < 0.001 |
| Post-surgical RT (B) | 45 | 3.48 | 0.54 | 1.35 | 0.52 | P < 0.001 | |||
| Post-surgical CRT (C) | 45 | 3.88 | 0.34 | 2.48 | 0.50 | P < 0.001 | |||
| Total | 135 | 3.28 | 0.81 | 1.48 | 0.95 | P < 0.001 | |||
| PD | Surgery (A) | 45 | 1.06 | 0.49 | A < B < C (p < 0.001) | 0.33 | 0.47 | A < B < C (p < 0.001) | P < 0.001 |
| Post-surgical RT (B) | 45 | 2.66 | 0.90 | 1.35 | 0.52 | P < 0.001 | |||
| Post-surgical CRT (C) | 45 | 3.64 | 0.48 | 2.02 | 0.54 | P < 0.001 | |||
| Total | 135 | 2.45 | 1.25 | 1.23 | 0.86 | P < 0.001 | |||
| PhD | Surgery (A) | 45 | 1.37 | 0.49 | A < B < C (p < 0.001) | 0.44 | 0.54 | A < B < C (p < 0.001) | P < 0.001 |
| Post-surgical RT (B) | 45 | 2.93 | 0.61 | 1.40 | 0.49 | P < 0.001 | |||
| Post-surgical CRT (C) | 45 | 3.86 | 0.31 | 2.40 | 0.61 | P < 0.001 | |||
| Total | 135 | 2.73 | 1.14 | 1.41 | 0.97 | P < 0.001 | |||
| MD | Surgery (A) | 45 | 0.91 | 0.51 | A < B < C (p < 0.001) | 0.33 | 0.47 | A < B, A < C (p < 0.001); B < C (p = 0.048) |
P < 0.001 |
| Post-surgical RT (B) | 45 | 2.02 | 0.83 | 1.40 | 1.55 | P = 0.021 | |||
| Post-surgical CRT (C) | 45 | 2.75 | 0.90 | 1.91 | 0.66 | P < 0.001 | |||
| Total | 135 | 1.89 | 1.08 | 1.21 | 1.20 | P < 0.001 | |||
| SD | Surgery (A) | 45 | 0.95 | 0.20 | A < B < C (p < 0.001) | 0.20 | 0.40 | A < B < C (p < 0.001) | P < 0.001 |
| Post-surgical RT (B) | 45 | 1.97 | 0.83 | 1.02 | 0.45 | P < 0.001 | |||
| Post-surgical CRT (C) | 45 | 2.84 | 0.82 | 1.80 | 0.66 | P < 0.001 | |||
| Total | 135 | 1.92 | 1.03 | 1.00 | 0.83 | P < 0.001 | |||
| H | Surgery (A) | 45 | 1.11 | 0.85 | A < B < C (p < 0.001) | 0.28 | 0.45 | A < B < C (p < 0.001) | P < 0.001 |
| Post-surgical RT (B) | 45 | 2.84 | 0.70 | 1.17 | 0.53 | P < 0.001 | |||
| Post-surgical CRT (C) | 45 | 3.53 | 0.62 | 2.35 | 0.64 | P < 0.001 | |||
| Total | 135 | 2.49 | 1.25 | 1.27 | 1.01 | P < 0.001 | |||
| overall | Surgery (A) | 45 | 10.55 | 2.26 | A < B < C (p < 0.001) | 2.80 | 2.40 | A < B < C (p < 0.001) | P < 0.001 |
| Post-surgical RT (B) | 45 | 20.20 | 3.80 | 13.62 | 5.64 | P < 0.001 | |||
| Post-surgical CRT (C) | 45 | 24.57 | 2.62 | 18.44 | 4.73 | P < 0.001 | |||
| Total | 135 | 18.44 | 6.57 | 11.62 | 7.92 | P < 0.001 | |||
OSCC: Oral squamous cell carcinoma; RT: Radiotherapy, CRT: Chemo-radiotherapy; FL: Functional limitation; PP: Physical pain; PD: Psychological discomfort; PhD; Physical disability; MD: Mental disability; SD: Social disability; H: Handicap; SD: standard deviation.