Table 4.
Correlation of histopathological grading and clinical staging with post-treatment general and oral health related quality of life.
| Parameters | N | OHIP-14 |
SF-12 |
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|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PCS |
MCS |
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| 1-month post-treatment |
6-months post-treatment |
1-month post-treatment |
6-months post-treatment |
1-month post-treatment |
6-months post-treatment |
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| mean | SD | mean | SD | mean | SD | mean | SD | mean | SD | mean | SD | |||
| Histopatho-logical grading | WDSCC (A) | 37 | 11.27 | 3.54 | 3.64 | 4.47 | 68.24 | 24.31 | 79.22 | 22.87 | 71.35 | 11.22 | 79.59 | 11.07 |
| MDSCC (B) | 84 | 21.38 | 5.49 | 14.98 | 7.11 | 58.25 | 25.28 | 72.39 | 26.18 | 54.76 | 14.53 | 70.77 | 14.15 | |
| PDSCC (C) | 14 | 19.78 | 3.78 | 12.50 | 3.77 | 74.10 | 4.14 | 92.41 | 6.09 | 61.78 | 4.64 | 80.00 | 4.38 | |
| p-value | B > A (p<0.001), C>A (p<0.001), B>C (p = 0.496) |
B > A (p<0.001), C>A (p<0.001), B>C (p = 0.351) |
B > A (p = 0.088), C > A (p = 0.712), B < C (p = 0.058) |
B < A (p = 0.323), C > A (p = 0.191), B < C (p = 0.013) |
B < A (p < 0.001), C < A (p = 0.054), B < C (p = 0.152) |
B < A (p = 0.002), C > A (p = 0.994), B < C (p = 0.035) |
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| Clinical TNM Staging | Stage I (A) | 16 | 10.00 | 2.25 | 2.18 | 2.31 | 73.82 | 20.31 | 82.03 | 20.26 | 75.93 | 4.55 | 82.50 | 5.77 |
| Stage II (B) | 17 | 11.00 | 2.17 | 3.11 | 2.44 | 65.44 | 27.43 | 77.20 | 25.85 | 69.70 | 14.83 | 79.41 | 14.56 | |
| Stage III (C) | 24 | 15.75 | 6.25 | 9.41 | 7.84 | 66.92 | 20.06 | 81.51 | 17.62 | 64.16 | 13.40 | 77.29 | 8.59 | |
| Stage IV (D) | 78 | 22.62 | 3.81 | 16.08 | 5.70 | 58.41 | 24.89 | 73.39 | 26.86 | 53.39 | 12.49 | 70.32 | 14.08 | |
| p-value | A < B (p = 0.895), A < C (p < 0.001), A < D (p < 0.001), B < C (p = 0.002), B < D (p < 0.001), C < D (p < 0.001) |
A < B (p = 0.964), A < C (p = 0.001), A < D (p < 0.001), B < C (p = 0.003), B < D (p < 0.001), C < D (p<0.001). |
A>B (p = 0.747), A > C (p = 0.809), A > D (p = 0.093), B < C (p = 0.997), B > D (p = 0.693), C > D (p = 0.427 |
A > B (p = 0.943), A > C (p = 1.000), A > D (p = 0.579), B < C (p = 0.946), B > D (p = 0.939), C > D (p = 0.495) |
A > B (p = 0.472), A > C (p = 0.019), A > D (p<0.001), B>C (p = 0.493), B > D (p<0.001), C>D (p = 0.002) |
A > B (p = 0.896), A > C (p = 0.578), A > D (p = 0.003), B > C (p = 0.952), B > D (p = 0.040), C > D (p = 0.089) |
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WDSCC: Well differentiated squamous cell carcinoma; MDSCC: Moderately differentiated squamous cell carcinoma; PDSCC: Poorly differentiated squamous cell carcinoma; SD: standard deviation.