Table 1.

Rituximab (RTX) binding stability at 10 nM and 60 nM was studied in the presence of unlabeled mAb in solution.

Cell line	RTX conc	kd (1/s)	Half-life (min)	Fold change half-life
Ramos	10 nM	3.32E-05	348
	60 nM	7.54E-05	153	0.44
Daudi	10 nM	7.17E-05	161
	60 nM	1.28E-04	90	0.56
P493.6	10 nM	4.97E-05	232
	60 nM	1.03E-04	112	0.48
LCL1.11	10 nM	5.14E-05	225
	60 nM	9.69E-05	119	0.53

The first 2 h of dissociation were used to calculate dissociation rate constants and corresponding half-lives.