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. 2021 Jan 11;14:614248. doi: 10.3389/fnsys.2020.614248

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Copyright © 2021 Liu, Narasimhan, Schriver and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Measurement of ECG from a wireless implant in awake animals. (A) Photo of a rat with a wireless electrocardiogram (ECG) implant. (B) Representative heart rate fluctuation throughout behavioral tasks. Insets: ECG traces during low and high heart rate periods. (C) Boxplots of fluctuation range of heart rate and heart rate variability across all sessions. (D) Histogram of heart rate. Error bars indicate SEM. (E) Negative correlation between heart rate and heart rate variability of an example session. n = 1,148 segments. (F) Box plots of the slope of correlation between heart rate and heart rate variability across all sessions.