Table 2.
Performance of the Proposed Radiogenomics Pipeline for Detection of IDH, 1p/19q, and EGFRvIII Markers of Gliomas in Terms of Various Performance Measures
| Configurations | Collection | Accuracy | Sensitivity | Specificity | Balanced accuracy (BAC) |
|---|---|---|---|---|---|
| Configuration I | |||||
| 1p/19q codeletion | TCIA | 75.15 | 81.49 | 73.96 | 77.73 |
| IDH mutation | TCIA | 85.45 | 82.80 | 87.68 | 85.24 |
| EGFRvIII mutation | HUP | 86.74 | 84.91 | 87.50 | 86.20 |
| Configuration II | |||||
| IDH mutation | TCIA + HUP + OBTS | 82.50 | 70.43 | 88.32 | 79.37 |
| Configuration III | |||||
| IDH mutation | TCIA (discovery) + HUP (replication) | 84.88 | 60.00 | 91.43 | 75.71 |