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(Top Row) Multi-parametric MRI is used to annotate the tumor subcompartments in GBM patients. The GBM tumor habitat consists of (1) necrotic core, (2) enhancing tumor, and (3) edema. Haralick features such as entropy and IDM are extracted from the GBM tumor habitat. (Bottom Row) Deformation features are calculated from the brain around tumor region. CoLlAGe gradients detect the homogeneous and heterogeneous regions based on the local intensity patterns on MRI scans.
