Table 1.
Condition | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
PEEP/VTset | 0/5 | 0/10 | 0/15 | 5/5 | 5/10 | 5/15 | 10/5 | 10/10 | 10/15 | 15/5 | 15/10 | 15/15 |
VTSpiro (ml) |
1932.93 (1689.87- 2176) |
3585.64 (3176.37- 3994.90) |
5197.60 (4536.40–5858.80) |
2193.00 (1924.91–2461.09) |
3879.76 (3419.59–4339.93) |
5482.48 (4833.65–6131.31) |
2275.78 (1985.26–2566.31) |
4054.08 (3534.26–4573.90) |
5367.29 (4728.03–6006.55) |
2237.50 (1985.24–2489.76) |
3797.76 (3158.72–4436.80) |
4989.20 (4355.00–5623.40) |
VTEIT (AU) |
2.24 (1.99–2.49) |
3.99 (3.63–4.36) |
5.71 (5.16 -6.25) |
2.29 (2.05–2.53) |
4.084 (3.73–4.44) |
5.57 (5.06–6.09) |
2.22 (1.98–2.46) |
3.99 (3.67–4.31) |
5.36 (4.81–5.91) |
2.21 (1.95–2.46) |
3.56 (3.12–4.00) |
4.77 (4.23–5.31) |
PIP* (cmH2O) |
18.14 (14.74–21.54) |
30.69 (28.26- 33.12) |
40.52 (37.32- 43.72) |
19.28 (18.20–20.35) |
33.51 (31.09–35.93) |
43.23 (40.50–45.96) |
23.07 (21.90–24.13) |
36.53 (34.41–38.65) |
47.95 (44.31–51.59) |
27.17 (26.06–28.17) |
41.39 (38.34–44.44) |
52.00 (48.74–55.26) |
VDPhys (ml) |
769.65 (701.84–837.47) |
944.20 (844.87–1043.52) |
1150.67 (886.64–1414.70) |
817.40 (737.29–897.51) |
948.22 (855.17–1041.27) |
1043.71 (927.65–1159.78) |
859.78 (774.11–945.45) |
988.17 (891.08–1085.26) |
1093.17 (1024.93–1161.41) |
899.43 (816.96–981.90) |
1050.40 (919.64–1181.16) |
1068.14 (990.59–1145.68) |
VDAw (ml) |
765.57 (691.78–839.37) |
911.94 (808.14- 1015.73) |
998.88 (853.79–1143.97) |
789.48 (709.07–869.88) |
917.84 (791.11–1044.57) |
1019.55 (870.19–1168.92) |
836.50 (741.20–931.81) |
961.16 (835.30–1087.02) |
1077.65 (973.913- 1181.39) |
875.64 (779.79–971.48) |
1047.81 (890.87–1204.74) |
1040.25 (926.33–1154.16) |
HR (bpm) |
58 (48–67) |
59 (49–69) |
56 (45–66) |
56 (44–68) |
56 (45–67) |
54 (44–63) |
52 (42–61) |
51 (40–61) |
51 (42–59) |
47 (37–57) |
46 (37–55) |
50 (40–60) |
mPAP (mmHg) |
16.5 (12.69–20.40) |
17.55 (13.39–21.70) |
17.64 (13.60–21.67) |
17.64 (14.14–21.13) |
18.45 (14.78–22.13) |
18.73 (14.87–22.59) |
18.45 (15.41–21.49) |
19.91 (16.43–23.39) |
20.80 (17.03–24.57) |
19.64 (16.55–22.72) |
20.18 (15.63–24.74) |
21.56 (16.89–26.23) |
MAP (mmHg) |
129.42 (112.81–146.02) |
121.67 (94.27–149.07) |
125.83 (108.52–143.14) |
126.42 (109.08–143.75) |
126.17 (108.63–143.71) |
122.25 (104.41–140.09) |
120.75 (101.17–140.33) |
117.42 (99.24–135.40) |
120.36 (104.04–136.69) |
108.08 (90.70–125.47) |
107.50 (89.37- 125.63) |
111.70 (94.03–129.37) |
Italics indicate Confidence Intervals in brackets
VTset ventilator tidal volume ml kg−1, VT Spiro tidal volume spirometry, VTEIT tidal volume electrical impedance tomography, PIP peak inspiratory pressure, VD Phys physiologic dead space, VD Aw airway dead space, HR heart rate, mPAP mean pulmonary artery pressure, MAP mean arterial pressure
*significant effect (p < 0.05)